Materials for On the gene ranking of replicated microarray time course data
نویسندگان
چکیده
In contrast, when ν → 0, the posterior odds are just equation (5) with ν replaced by 0. This means that gene-specific Ws are so different such that moderation is not able to move these gene-specific W at all. Thus, the degree of moderation reflects how similar these gene-specific within group sums of squares are. The more similar they are, the greater degree of moderation our proposed statistic can perform.
منابع مشابه
On the gene ranking of replicated microarray time course data
Consider the gene ranking problem of replicated microarray time course experiments where there are multiple biological conditions, and genes of interest are those whose temporal profiles are different across conditions. We derive the multi-sample multivariate empirical Bayes statistic for ranking genes in the order of differential expression, from both longitudinal and cross-sectional replicate...
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